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  • SF Defensive End #97
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    Nick Bosa (hip/oblique) did not practice on Wednesday.
    Bosa had been rehabilitating a combination hip and oblique injury for weeks, entering Week 11. He pulled up lame in-game while rushing the passer and was later reported to have strained his other oblique. Bosa’s inability to participate on Wednesday was expected but is still concerning. He is truly questionable for Week 12.
  • SF Quarterback #13
    Brock Purdy (shoulder) was limited in Wednesday’s practice.
    Per head coach Kyle Shanahan, Purdy is dealing with soreness in his right (throwing) shoulder after the team’s Week 11 loss to the Seahawks. Shanahan is hardly a reliable narrator when it comes to injuries, but this does appear to be a rather minor issue. Barring a surprise, Purdy will suit up as a low-end QB1 for his Week 12 matchup with the Packers.
  • SF Tight End #85
    George Kittle (hamstring) was limited in Wednesday’s practice.
    Kittle missed Week 11 with the hamstring issue despite closing the week with two limited practices before being listed as questionable. A limited practice to open the week is a step in the right direction. Head coach Kyle Shanahan also told reporters that he was close to playing on Sunday. Our bet is on Kittle returning for Week 12 and Kittle evidently agrees, telling reporters “I will be playing on Sunday.” Fantasy managers will want to keep tabs on this situation as the week progresses but things are headed in the right direction. The 49ers don’t have a tight end of note for fantasy purposes when Kittle is sidelined, so emergency Kittle replacements will need to come from other squads.
  • SF Quarterback #13
    49ers coach Kyle Shanahan said Brock Purdy came out of Week 11’s game against Seattle with “soreness in his right shoulder.”
    In other words, it wouldn’t be a surprise to see him on the injury report this week. Shanahan said much the same thing about George Kittle’s hamstring after Week 10, before he missed Week 11. We wouldn’t bet on Purdy missing a game, to be clear, but this should at least open the door to some question about his Week 12 status.
  • SF Tight End #85
    49ers coach Kyle Shanahan said George Kittle was “close” to playing against the Seahawks in Week 11 and should be able to practice Wednesday.
    Kittle was officially questionable last week with the hamstring injury, and was supposedly going to test it in pre-game workouts but was declared inactive without even getting on the field before the game. This is good news, but limited practices won’t exactly bring us any closer to a conviction that Kittle will play in Week 12.
  • SF Defensive End #97
    49ers HC Kyle Shanahan said DE Nick Bosa (hip/oblique) will be “evaluated through the week.”
    Bosa injured his hip and oblique in the team’s Week 11 loss to the Seahawks, raising concerns after the veteran pass rusher came into the week with oblique discomfort. The new injury is reportedly on the other side, with initial reports indicating it could be a “compensation injury,” meaning the other muscles surrounding the affected area were working to overcome an injury elsewhere. Fans will want to keep an eye on his status after a devastating loss that dropped the 49ers into last place in the NFC West.
  • SF Running Back #24
    Jordan Mason rushed two times for 13 yards in the 49ers’ Week 11 loss to the Seahawks.
    Mason has been fully relegated to that of an elite bench stash, with Christian McCaffrey now dominating touches out of the backfield. Mason fumbled on a kick return attempt but smartly chased the ball down and swatted it out of bounds before the Seahawks’ coverage team could close on it. Mason should not be started against the Packers in Week 12.
  • SF Running Back #23
    Christian McCaffrey rushed 19 times for 79 yards and caught 4-of-5 targets for 27 yards in the 49ers’ Week 11 loss to the Seahawks.
    The high-scoring fantasy outings should eventually come; McCaffrey’s 42 touches over the last two weeks are more than double that of the next closest 49er. Perhaps the most telling sequence of McCaffrey’s current state occurred as he ran onto the field for the 49ers’ second drive, where he could be seen aggressively driving his feet into the ground, transferring his weight side-to-side as he did so. The talented veteran running back is still trying to find his footing as he returns from bilateral Achilles tendonitis but his two setback-free showings should be taken as a net positive. He is an RB1 against the Packers in Week 12.
  • SF Wide Receiver #14
    Ricky Pearsall caught 0-of-2 targets in the 49ers’ Week 11 loss to the Seahawks.
    This was a sad showing for Pearsall, who had a chance to produce as the team’s No. 3 or 4 pass catcher with George Kittle sidelined. Pearsall completely flopped though, relegating him to that of a shaky bench stash option moving forward.
  • SF Defensive End #97
    Fangirl Sports’ Tracy Sandler reports Nick Bosa suffered a second oblique strain while sacking Geno Smith in Week 11.
    Bosa entered Week 11 dealing with a nagging hip injury but the in-game broadcast revealed that Bosa is bothered far more by the injury’s oblique-muscle component than his actual hip. Per Sandler, things took a turn for the worse in Week 11, saying “Bosa said he overcompensated on that second sack and now both obliques are hurting.” Sandler adds, Bosa “has some level of concern that he’s going to have to miss some time” as a result. The 49ers appear likely to be without their star defender against the Packers in Week 12.