The 49ers played the role of playoff spoiler last season, making it to the Conference Championship as a six seed before losing to the Rams, who would go on to win Super Bowl LVI. The team’s quarterback picture remains unclear heading into 2022, with Jimmy Garoppolo and Trey Lance both seemingly in contention for the starting job. Now that the full 18-week 2022 NFL schedule has been released, keep reading to see the 49ers’ full schedule, including dates, times, opponents, primetime games and more. Coverage of the latest news from around the NFL is available all year round on PFT’s Peacock channel.
- 49ers 2021 record: 10-7 (lost Conference Championship)
- Head coach: Kyle Shanahan
- Key players: Jimmy Garoppolo (QB), George Kittle (TE), Nick Bosa (DE)
- 49ers 2022 NFL draft results
RELATED: 2022 Sunday Night Football schedule | Thanksgiving NFL schedule 2022 | Week 1 2022 NFL schedule
49ers schedule 2022 (all times Eastern)
- Week 1: 9/11 Bears 19, 49ers 10 [recap]
- Week 2: 9/18 49ers 27, Seahawks 7 [recap]
- Week 3: 9/25 Broncos 11, 49ers 10 [recap]
- Week 4: 10/3 49ers 24, Rams 9 [recap]
- Week 5: 10/9 49ers 37, Panthers 15 [recap]
- Week 6: 10/16 Falcons 28, 49ers 14 [recap]
- Week 7: 10/23 Chiefs 44, 49ers 23 [recap]
- Week 8: 10/30 49ers 31, Rams 14 [recap]
- Week 9: BYE
- Week 10: 11/13 49ers 22, Chargers 16 [recap]
- Week 11: 11/21 49ers 38, Cardinals 10 [recap]
- Week 12: 11/27 49ers 13, Saints 0 [recap]
- Week 13: 12/4 49ers 33, Dolphins 17 [recap]
- Week 14: 12/ 11 49ers 35, Buccaneers 7 [recap]
- Week 15: 12/15 49ers 21, Seahawks 13 [recap]
- Week 16: 12/24 49ers 37, Commanders 20 [recap]
- Week 17: 1/1 49ers 37, Raiders 34 [recap]
- Week 18: 1/8 49ers 38, Cardinals 13 [recap]
- Wild Card: 1/14 49ers 41, Seahawks 23 [recap]
- NFC Divisional: 49ers 19, Cowboys 12 [recap]
- NFC Championship: Eagles 31, 49ers 7 [recap]
Prime-time games
- Sunday Night Football: Week 3 at Broncos, Week 10 vs. Chargers
- Monday Night Football: Week 4 vs. Rams, Week 11 vs. Cardinals (Mexico City)
- Thursday Night Football: Week 15 at Seahawks
RELATED: 2022 NFL schedule: All 32 teams’ home openers
Check out every teams’ 2022 NFL schedule below:
NFC: East (DAL | NYG | PHI | WAS), North (CHI | DET | GB | MIN), South (ATL | CAR | NO | TB), West (ARI | LAR | SF | SEA)
AFC: East (BUF | MIA | NE | NYJ), North (BAL | CIN | CLE | PIT), South (HOU | IND | JAX | IND), West (DEN | KC | LV | LAC)
