The Colts scored 24 unanswered points after falling behind 7-0 as they seek to keep their playoff hopes alive.
Jonathan Taylor rushed for 119 yards in the first half, leading the Colts to a 24-7 halftime lead over the Titans.
The Colts have outgained the Titans 274 to 141, and they used Kenny Moore’s pick of Mason Rudolph for a touchdown on a short field before the half.
Moore returned the interception 12 yards to the Tennessee 33 on a pass intended for Tyler Boyd. Three plays later, Anthony Richardson hit Josh Downs for a 27-yard touchdown.
Richardson is 5-of-8 for 90 yards with a touchdown and an interception and has rushed for 56 yards and a touchdown on six carries. Taylor has 15 carries, one of which he took 65 yards for a touchdown.
Rudolph is 10-of-16 for 111 yards with a touchdown and an interception, with Calvin Ridley catching two for 57 yards and a touchdown.
