The Buccaneers led by seven points at the half. They lead by 16 at the end of the third quarter.
Tampa Bay scored a safety on an intentional grounding call on Jalen Hurts in the end zone and then used the free kick for a two-play, 62-yard touchdown drive.
Rookie Trey Palmer caught a short pass from Baker Mayfield and ran 56 yards to the end zone, with James Bradberry missing a tackle that would have limited Palmer to a short gain.
The Bucs lead 25-9.
Baker Mayfield is 16-of-30 for 259 yards and two touchdowns.