The Bills officially placed defensive lineman Dawuane Smoot on injured reserve, the team announced Tuesday.
Smoot has a wrist injury that requires surgery.
He has played all along the defensive line, totaling 12 tackles, three tackles for loss, 1.5 sacks and a forced fumble in seven games this season.
Coach Sean McDermott said Monday he is hopeful Smoot can return this season.
Smoot will have to miss a minimum of four games before returning to the active roster.
