The Indianapolis Colts (2-2) and the Pittsburgh Steelers (2-2) both enter Sunday’s matchup at Acrisure Stadium looking to climb above .500 in a crowded AFC playoff race. The Steelers have alternated wins and losses through four weeks while the Colts have won their last two after dropping a pair to open the campaign.
Daniel Jones and the Colts currently sit second in the AFC South one game behind Trevor Lawrence and the Jacksonville Jaguars. Aaron Rodgers and the Steelers are tied for third in the AFC North with Joe Burrow and the Bengals.
Indianapolis heads into Week 5 with momentum after a convincing 30-13 victory over Washington in London. Jonathan Taylor was the No. 1 star for the Colts rushing for 95 yards and a couple of scores on 20 carries. Daniel Jones was solid, completing 19 of 34 passes for 143 yards to seven different receivers. He also scored a touchdown himself on the ground. Yes, Indy took advantage of the Commanders playing most of the game with their third-string quarterback, Athan Kaliakmanis. Pittsburgh, meanwhile, is coming off a frustrating 27-24 loss to the Browns on Thursday Night Football. The Steelers never led last Thursday in their loss at Cleveland, but did tie it with under two minutes to play only to lose with ten seconds left in regulation. Aaron Rodgers threw for 299 yards and DK Metcalf hauled in five passes for 115 yards but the defense could not stop the rejuvenated Deshaun Watson and what had been a lethargic Browns’ offense.
One of the biggest storylines will be whether Indianapolis can continue its productive ground attack against T.J. Watt and a Steelers’ defense, while Pittsburgh will try to capitalize on a Colts’ team that has struggled with turnovers and an inconsistent passing attack early in the season.
Historically, this has been a Steelers-dominated series. Pittsburgh owns a 28-8 all-time advantage over Indianapolis, including several memorable postseason meetings. The most recent matchup came on November 2, 2025, when the Steelers defeated the Colts 27-20 in Pittsburgh. The Steelers’ defense forced four Daniel Jones turnovers, overcoming a first-quarter deficit for the victory.
With both teams sitting at 2-2 and playoff positioning already becoming important in the AFC, Sunday’s game carries the feel of an early-season measuring-stick for two clubs trying to establish themselves as legitimate postseason contenders.
Let’s dive into the numbers and see if we can’t find an additional sweat or two.
NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.
Game Details and How to Watch: Colts vs. Steelers
- Date: Sunday, October 11, 2026
- Time: 1PM ET
- Site: Acrisure Stadium
- City: Pittsburgh, PA
- TV/Streaming: CBS
Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.
Latest Game Odds: Colts vs. Steelers
The latest odds as of Tuesday courtesy of DraftKings:
- Moneyline: Indianapolis Colts (+114), Pittsburgh Steelers (-135)
- Spread: Steelers -2.5
- Total: 44.5
The Total has dropped a full three points since opening at 47.5, but the Spread is right where it opened.
Peacock offers one of the most comprehensive live sports streaming lineups available today, bringing together the NFL, NBA, MLB, WNBA, Premier League, NCAA football, NCAA basketball, golf, motorsports, and major global sporting events in a single service.
Rotoworld Bet Best Bets
Expert Picks & Predictions: Colts vs. Steelers
Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.
Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, betting trends, and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Sunday’s game between the Colts and the Steelers:
- Moneyline: NBC Sports is leaning towards a play on the Steelers on the Moneyline.
- Spread: NBC Sports is staying away from a play involving the Spread.
- Total: NBC Sports is recommending a play on the Game Total OVER 44.5.
Here’s why the OVER is worth a look:
The line has been bet down from 47.5 to 44.5 — a three-point drop that reflects the market overcorrecting on the low side. The Colts have allowed 26.0 points per game this season, and two of their four games have gone past 60 total points. Their defense ranks 22nd in opponent EPA per play and dead last in Net Yards per Play. In a game with two leaky defenses, two offenses that can move the ball, and a rest discrepancy that favors the home team’s scoring, this has all the makings of a higher-scoring, back-and-forth affair.
Colts vs. Steelers: Betting Trends and Stats
- The Colts are 3-1 against the spread this season
- The Steelers are 2-2 against the spread this season
- Indianapolis is 2-2 to the OVER this season
- Pittsburgh is 2-2 to the OVER this season
Quarterback Matchup: Colts vs. Steelers
- Indianapolis: Daniel Jones
2026 Statistics: 4GP, 754 Passing Yards, 3 TDs, 4 INTs, 73.9 RTG, Sacked 8 times - Pittsburgh: Aaron Rodgers
2026 Statistics: 4GP, 999 Passing Yards, 7 TDs, 4 INTs, 81.6 RTG, Sacked 13 times
Colts vs. Steelers: Top Playmakers
Colts
- RB Jonathan Taylor
2026 Statistics: 4GP, 86 carries for 353 Yds, 6 TDs / 10 receptions on 15 targets for 69 Yds, 0 TDs - TE Tyler Warren
2026 Statistics: 4GP, 23 receptions on 27 targets for 130 Yds, 2 TDs - WR Josh Downs
2026 Statistics: 4GP, 17 receptions on 28 targets for 202 Yds, 0 TDs
Steelers
- WR DK Metcalf
2026 Statistics: 4GP, 16 receptions on 33 targets for 213 Yds, 1 TD - RB Jaylen Warren
2026 Statistics: 4GP, 55 carries for 309 Yds, 0 TDs / 13 receptions on 19 targets for 143 Yds, 0 TDs - TE Pat Freiermuth
2026 Statistics: 4GP, 14 receptions on 20 targets for 125 Yds, 2 TDs
Colts vs. Steelers: Injury Update
Colts
- WR Keenan Allen (undisclosed) is listed as questionable for Sunday’s game
- DE Arden Key (hamstring) is listed as out for Sunday’s game
Steelers
- RB Rico Dowdle (toe) is listed as questionable for Sunday’s game
- CB Jamel Dean (ankle) is listed as doubtful for Sunday’s game
Rotoworld still has you covered with all the latest and tools for the NFL, including game predictions, player props, futures, and trends!
Follow our experts on socials to keep up with all the latest content from the staff:
- Jay Croucher (@croucherJD)
- Vaughn Dalzell (@VmoneySports)
- Drew Dinsick (@whale_capper)
- Trysta Krick (@Trysta_Krick)
