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Patriots at Bills prediction: Odds, expert picks, QB matchup, injury report, betting trends, and stats

Drake Maye and the last place New England Patriots (3-11) travel to Orchard Park for an AFC East battle against Josh Allen and the division-leading Buffalo Bills (11-3).

Allen and co. have already clinched the division crown. They still have an outside shot for the top overall seed in the AFC. That said, is there a possibility the Bills suffer a bit of a letdown this week following a stretch that has seen them defeat the Chiefs and Lions?

Yes, the Patriots have struggled mightily this season. Drake Maye, however, looks more and more like a player who can lead this franchise for the next decade. The rookie out of North Carolina has thrown 12 TD passes and 9 INTs while going 2-7 as the starter.

This is the first of two meetings on the schedule between these teams this season. They meet again in two weeks in Foxborough. Buffalo has won 7 of the last 9 games against New England.

Lets dive into the matchup and find a sweat or two.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.

Listen to the Bet the Edge podcast as hosts Jay Croucher and Drew Dinsick provide listeners with sharp actionable insight, market analysis and statistical data to help bettors gain more information before placing their wagers. So, whether you’re targeting spreads and totals, looking for value in futures markets or circling player props, give their podcast a listen to give you that extra edge.

Game details and how to watch Patriots at Bills

· Date: December 22, 2024
· Time: 4:25 PM ET
· Site: Highmark Stadium
· City: Orchard Park, NY
· TV/Streaming: CBS

Latest Game Odds for Patriots at Bills

The latest odds courtesy of DraftKings:
· Moneyline: New England Patriots (+650), Buffalo Bills (-1000)
· Spread: Bills -14
· Total: 46.5
Little movement on the Line and the Total over the course of the week. In fact, both sit right where they opened this week.

NBC Sports Bet Best Bets

Expert picks & predictions for Patriots at Bills

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, betting trends, and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Sunday’s game between New England and Buffalo:

  • Moneyline: NBC Sports is recommending a play on the Bills on the Moneyline
  • Spread: NBC Sports is recommending a play ATS on the Bills.
  • Total: NBC Sports is recommending a play on the Total OVER 46.5.

Patriots at Bills Stats, Betting Trends

· The Patriots are 5-8-1 against the spread this season.
· The Patriots are 9-5 to the OVER this season.
· The Bills are 9-5 against the spread this season.
· The Bills are 9-5 to the OVER this season.
· The Bills are 7-3 against the spread in their last 10 games.
· The Bills have won 6 games straight at home, while the Patriots have lost on 7 of their last 9 on the road.
· The Patriots’ last 3 road games at the Bills have gone OVER the Total.

Quarterback Matchup for Patriots at Bills

· New England: Drake Maye – completed 19 of 23 passes for 202 yards in last week’s loss at Arizona. Has been sacked in every game he has played this season and 27 times in total (10 games).
· Buffalo: Josh Allen – the MVP favorite (-900) has 25 TDs and 5 INTs this season. The Bills’ have scored at least 30 points in 8 straight games and eclipsed the 40-point mark 3 times this season.

Patriots at Bills Injury Report

  • New England CB Christian Gonzalez (shoulder) is questionable for Sunday’s game.
  • New England WR Javon Baker (concussion) is questionable for Sunday’s game.
  • New England S Kyle Dugger (ankle) is questionable for Sunday’s game.
  • New England RB Jamycal Hasty (ankle) is questionable for Sunday’s game.
  • New England CB Marcus Jones (hip) is questionable for Sunday’s game.
  • Buffalo CB Rasul Douglas (knee) is questionable for Sunday’s game.
  • Buffalo S Damar Hamlin (ribs) is questionable for Sunday’s game.
  • Buffalo LB Matt Milano (biceps) is questionable for Sunday’s game.
  • Buffalo S Taylor Rapp (neck) is questionable for Sunday’s game.

Rotoworld still has you covered with all the latest and tools for the NFL, including game predictions, player props, futures, and trends!

Follow our experts on socials to keep up with all the latest content from the staff:
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· Jay Croucher (@croucherJD)
· Drew Dinsick (@whale_capper)