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Broncos vs Colts Prediction: Odds, Expert Picks, QB Matchup, Injury News, Betting Trends and Stats

Seahawks, Colts lead best bets for NFL Week 15
Drew Dinsick and Jay Croucher provide their best bets for NFL Week 15, including the Seahawks and Colts beating the spread in their respective matchups.

The Broncos and Colts meet in a matchup of playoff hopefuls in the AFC coming off bye weeks.

The Colts are 6-7 and coming off a comeback win over the Patriots (25-24) before hitting the bye week. Indianapolis has a very winnable path to make the playoffs, but this road test at Denver will be the toughest of the remaining four games (Titans, Giants, Jaguars). Indianapolis is 3-4 away from home and won two straight on the road.

Denver is 8-5 and a winner in three straight. Like the Colts, the Broncos are coming off a bye week to regroup. Denver plays the Chargers, Bengals, and the Chiefs down the stretch, so this is arguably the most winnable game for the Broncos. Denver is 4-2 at home and won three straight and four of the past five at Mile High.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.

Listen to the Bet the Edge podcast as hosts Jay Croucher and Drew Dinsick provide listeners with sharp actionable insight, market analysis and statistical data to help bettors gain more information before placing their wagers.

Game Details and How to watch the Indianapolis Colts vs. Denver Broncos on Sunday

· Date: Sunday, December 15, 2024

· Time: 4:25 PM EST

· Site: Empower Field at Mile High

· City: Denver, CO

· TV/Streaming: CBS

Want to check out the other games on the NFL schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time, and TV/streaming info so you won’t miss any of the action!

Game odds for Colts vs. Broncos

The latest odds as of Friday courtesy of DraftKings:

Moneyline: Denver Broncos (-198), Indianapolis Colts (+164)

Spread: Broncos -4.5 (-110)

Total: 44.0

The spread opened Denver -4 and a total of 43.5 points, so the Over and Broncos have taken more of the handle. The Broncos are tied with the Steelers for an NFL-best 10-3 ATS.

Expert picks & predictions for Broncos vs Colts

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NBC Sports Bet Best Bet

Vaughn Dalzell (@VmoneySports) likes Anthony Richardson to go Under 0.5 Passing Touchdowns at +175 odds:

“Anthony Richardson has seven passing touchdowns to nine interceptions on the season and a horrid 47.4 completion percentage.

While Richardson has thrown at least one touchdown in three of the past four games, I think this is a good spot to fade him. Going to Denver presents a lot of issues, including fatigue due to elevation, in addition, the Broncos’ defense has performed at a top-10 unit all season.

The Colts are coming off a bye week, so I expect a lot of designed runs with winds expected to hit 10-20 MPH. WR Josh Downs is questionable and if he’s out, I like this prop even more.

Shop around because some places list Richardson Under 0.5 Passing Touchdowns at +125 to +150 odds and others are hanging +175.”

Rotoworld has you covered with all the latest betting info & tools for NFL with game predictions, player props, futures, and trends!

Denver Broncos vs. Indianapolis Colts team stats, betting trends

  • Denver is tied with Pittsburgh for an NFL-best 10-3 ATS record.
  • Indianapolis ranks top 10 ATS at 8-5 on the year.
  • The Colts are 4-1 ATS as a road underdog, ranking top five.
  • Denver is 4-0 ATS as a home favorite, which is the best.
  • The Broncos are 8-5 to the Over, while the Colts are 7-6 to the Under.
  • Bo Nix threw for at least 270 passing yards in three straight games.
  • Anthony Richardson had a season-high three total touchdowns last week.
  • Jonathan Taylor had 96 rushing yards last week. He has four 100 rushing yards performances this season.
  • Jaleel McLaughlin had 84 rushing yards last week and has taken over the backfield.
  • Cortland Sutton has six straight games of at least 70 yards.
  • Marvin Mims caught 105 of his 267 yards last week.

Quarterback matchup for Indianapolis vs. Denver

Indianapolis: Anthony Richardson – Richardson has 11 total touchdowns but seven passing to nine interceptions on the year. Richardson has failed to crack 200 passing yards in two straight games and six of the past seven.

Denver: Bo Nix - Nix is ranked second in odds for NFL Rookie of the Year behind Jayden Daniels. Nix has 20 total touchdowns (17 passing, 3 rushing) to eight interceptions along with 2,854 passing yards and a 63.8 completion percentage. Nix has nine touchdowns to two interceptions over the last four games.

Broncos and Colts injury update

Denver’s S Delarrin Turner-Yell (knee), CB Riley Moss (knee), and LB Drew Sanders (achilles) are out, while C Luke Wattenberg (ankle) is questionable.

For the Colts, OT Braden Smith (personal), WR Ashton Dulin (ankle), and DB Jaylon Carlies (knee) are out, while WR Josh Downs (shoulder), DE Tyquan Lewis (elbow), LB E.J. Speed (knee), and LB Cameron McGrone (elbow).

Rotoworld has you covered with all the latest betting info & tools for NFL with game predictions, player props, futures, and trends!

Follow our experts on socials to keep up with all the latest content from the staff:

Jay Croucher (@croucherJD)

Drew Dinsick (@whale_capper)

Vaughn Dalzell (@VmoneySports)

Brad Thomas (@MrBradThomas)