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Ohio State at USC Prediction: Odds, Expert Picks, Betting Trends and Stats

It’s a busy Wednesday in college basketball highlighted by tonight’s tilt in the Big Ten featuring the Ohio State Buckeyes (15-13, 7-10) and the Trojans of USC (14-13, 6-10).

USC is back home following losses last week at Rutgers and at Maryland. They have lost three in a row and five of their last six games.

Ohio State has also lost three in a row. They opened this West Coast trip with a 69-61 loss at UCLA.

Lets dive into the matchup and offer some information and possibly a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch the opening tip, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Game details & how to watch Ohio State at USC

  • Date: Wednesday, February 26, 2025
  • Time: 10:30PM EST
  • Site: Galen Center
  • City: Los Angeles, CA
  • Network/Streaming: BTN

Never miss a second of the action and stay up to date with all the latest scores and player news. Check out our day-by-day NCAA Basketball Schedule Page that includes live game updates.

Game odds for Buckeyes at Trojans

*odds courtesy of BetMGM

  • Odds: Buckeyes (-102), Trojans (-118)
  • Spread: Trojans -1.5
  • Total: 151.5 points

Bet the Edge is your source for all things sports betting. Get all of Jay Croucher and Drew Dinsick’s insight weekdays at 6AM ET right here or wherever you get your favorite podcasts.

Expert picks & predictions for Ohio State at USC

NBC Sports Bet Best Bet

Our model calculates projections around each moneyline, spread and over/under bet for every game on the NCAA calendar based on data points like past performance, player matchups, injuries, and the schedule.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for today’s Buckeyes & Trojans game:

  • Moneyline: NBC Sports Bet is recommending a play on the USC on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on USC at +1.5.
  • Total: NBC Sports Bet is recommending a play on the under on the Game Total of 151.5.

Buckeyes vs Trojans: Top betting trends and recent stats

  • Ohio State has lost 4 of its last 5 games
  • The Over is 13-7 in Ohio State’s and USC’s last 10 games combined
  • Ohio State has failed to cover in 5 of its last 7 games (71%)
  • USC has cashed the OVER in five of their last six games

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our NCAA Basketball Top Trends Tool on NBCSports.com!

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Follow our experts on socials to keep up with all the latest content from the staff:
· Jay Croucher (@croucherJD)
· Drew Dinsick (@whale_capper)
· Vaughn Dalzell (@VmoneySports)
· Brad Thomas (@MrBradThomas)

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Men's College Basketball