On Friday Kyle Shanahan provided an update on injuries to Nick Bosa and other key 49ers players.
As the 49ers take on Tom Brady and the Tampa Bay Buccaneers on Sunday, the seven-time Super Bowl-winning quarterback will have star defensive end Nick Bosa to worry about.
Bosa, who was listed as questionable on Friday's report with a hamstring injury, will play in the key NFC matchup at Levi's Stadium.
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The 49ers on Friday already had ruled out three players from participating in Sunday's game: Quarterback Jimmy Garoppolo (foot), defensive tackle Hassan Ridgeway (pectoral) and safety Tarvarius Moore (knee).
Tight end Ross Dwelley, linebacker Curtis Robinson, offensive lineman Nick Zakelj and running back Tyrion Davis-Price also are inactive Sunday, while running back Tevin Coleman and defensive back Dontae Johnson are active for the contest after being elevated from the practice squad on Saturday.
ESPN's Adam Schefter first reported on Saturday night that Bosa would play, citing a source.
Bosa did not practice with the 49ers this week. The NFC Defensive Player of the Month for November currently leads the NFL with 14.5 sacks through the 11 games he has played this season.
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The pass rusher previously missed San Francisco's Week 6 game against the Atlanta Falcons with a groin injury.
Bosa is coming off an incredible game against the Miami Dolphins in Week 13, where he tallied three sacks in the 33-17 win and was named the NFC Defensive Player of the Week.
As the 49ers and rookie quarterback Brock Purdy meet the Bucs fresh off their dramatic, come-from-behind win over the New Orleans Saints last week, San Francisco will need all the help it can get.
But if there's anyone who can spoil Brady's Bay Area homecoming, it's Bosa.
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As for the Buccaneers, they'll have seven players inactive on Sunday:
