Liverpool lead the way, while Aston Villa have the last top-eight spot and Premier League sides Arsenal and Manchester City are currently in the playoff places.
Christian Pulisic scored twice and the USMNT piled up the goals early to defeat Jamaica and advance to a fourth-straight CONCACAF Nations League semifinals.
Messi was targeted by Paraguayan attackers, fouled five times in a loss which comes just four days after his first foray into the MLS Cup Playoffs ended in a stunning upset.
Fulham keep climbing up the Premier League table, now boasting the fourth-most points in the division after a 2-0 win over Crystal Palace at Selhurst Park on Saturday.